The PrEggNut Study

Maternal diet rich in eggs and peanuts to reduce food allergies: a randomised controlled trial
The PrEggNut Study
Project Status: In progress
Project administered by: The University of Western Australia

Food allergies now affect more than 10% of children. Recently, babies have been found to be at risk of developing a food allergy even before they start eating solid foods. This team's earlier work has suggested that babies’ immune responses can be improved by their mothers eating more eggs during the first weeks of breastfeeding.

This research trial aims to determine whether mothers regularly eating more eggs and peanuts during pregnancy and breastfeeding will reduce food allergies in their babies.

Serious food allergy reactions, anaphylaxis and food-related deaths have increased over the past two decades. Food allergy is a chronic disease that reduces quality of life, places significant burdens on schools, communities and the health care system at large. Effective prevention strategies in early life are urgently needed.

SAHMRI is looking for people who are less than 23 weeks pregnant to participate in the PrEggNut Study

This randomised controlled trial study design will address an important gap in knowledge. It will provide high quality scientific outputs that progress the field of allergy prevention and will provide a sound evidence base to inform clinical practice allergy prevention recommendations for the role of regular inclusion of traditionally allergenic foods in the maternal diet during pregnancy and breastfeeding.

PrEggNut participant

What does the study involve?

Participants will be randomly assigned to one of two study groups: a ‘standard egg and peanut diet’ group (which is typical for most women) and a ‘high egg and peanut diet’ group. Participants will be asked to follow the diet advice for their group from 22 weeks gestation until their baby is 4 months of age (or until breastfeeding ceases). The outcomes of egg and peanut allergies will be compared in the babies of the two groups at 1 year of age.

Who is conducting the study?

The PrEggNut Study is being directed by Dr Debra Palmer at the Telethon Kids Institute in Perth. It is a large, multi-centred study being conducted in Adelaide through SAHMRI,

Who is eligible to participate?

Pregnant women who:

  • Are less than 23 weeks gestation (singleton pregnancy)
  • Have at least two family members (themselves, partner or child/ren) with or without a history of medically diagnosed allergic disease (asthma, eczema, hay fever or food allergy)
  • Plan to breastfeed for at least four months
  • Do not have egg or peanut allergy

Resources

Participant Information / Consent Form

Get in touch

This project is funded by the National Health and Medical Research Council