Professor Stuart Brierley

Prof Brierley is Director of the Visceral Pain Research Group and Director of the Hopwood Centre for Neurobiology, located at the South Australian Health and Medical Research Institute (SAHMRI). He is also an NHMRC R.D Wright Biomedical Fellow (CDF II).

In 2017 Prof Brierley was awarded an NHMRC Research Excellence Award for being the top Ranked CDF II in the 2016 round. He was also a South Australian Tall Poppy Science Awardee in 2011.

Prof Brierley is an international leader on the gut-brain axis. This includes the different afferent classes innervating the gut, the channels and receptors underlying their function and how this changes in acute and chronic pain. Prof Brierley has a proven track record in coordinating multi-faceted research programs for high-impact publications in journal such as Nature, Cell, Nature Communications, Gastroenterology, Gut, PNAS, JCI Insight, Pain, British Journal of Pharmacology and The Journal of Neuroscience. He also has invited reviews published in Nature Reviews Gastroenterology and Hepatology, Annual Reviews of Physiology, Gut, Trends in Biomedical Sciences, Journal of Physiology and The International Journal of Biochemistry & Cell Biology.

To date, Prof Brierley has been a CI on 13 NHMRC Project grants. He has also been awarded three (2008, 2013, 2016) prestigious NHMRC fellowships. He is also a CI on an ARC Discovery Grant and CI on 2 recently awarded 3-year NIH grants under the SPARC/HEAL schemes. He also has a strong track record of industry collaboration.

His recent collaborations with Industry partners identified the mechanism of pain relief of a new drug, linaclotide, in treating patient with Irritable Bowel Syndrome with Constipation (IBS-C). Linaclotide, a guanylate cyclase-C (GC-C) agonist is effective in relieving abdominal pain associated with IBS-C and is already available and registered for use by IBS-C patients in the USA and Europe.

For a current list of publications see: https://www.ncbi.nlm.nih.gov/pubmed/?term=brierley-sm

Key positions

• President of the Australasian Neurogastroenterology and Motility Association (ANGMA).
• Co-chair of the Federation of Neurogastroenterology and Motility (FNM) 2021 meeting in Adelaide.
• NHMRC R.D Wright Biomedical Fellow (CDF II; 2017-2020).
• NHMRC R.D Wright Biomedical Fellow (CDF I; 2013-2016).
• NHMRC Australian Biomedical Fellow (2008-2012).