The NINA Study

Effect of Nutritional Interventions on Autophagy

The NINA Study
Project Status: In progress
Project administered by: SAHMRI

What we eat affects the autophagy process that cleanses our cells of damaged molecules. This process slows biological ageing.

Autophagy is a recycling process that happens inside the cells that make up tissues in your body. Autophagy removes and degrades damaged and unwanted molecules and breaks them down into smaller parts that can be reused to build new cell parts.

Importantly, autophagy can be modified through nutrition in laboratory settings.

To properly answer questions about whether nutritional strategies can change autophagy in humans, our research group has developed a first-ever test to measure autophagy in human blood.

This project aims to measure the effect of diet composition on autophagy in blood, using two different diets designed by a qualified dietitian. This will provide information about whether autophagy responds to nutrition in humans, and if it does, how nutrition could be used to treat or prevent diseases known to be impacted by changes in autophagy such as Alzheimer's disease and heart disease.

Please note: this study is no longer recruiting participants.

If you have any questions about the NINA Study, please contact our team at or phone (08) 8128 4570 or 0491 718 286.

This project is funded by BrightFocus Foundation