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The Bloom Infant Probiotic (BIP) Study

A randomised controlled trial to assess if a probiotic intervention leads to enhanced immune responses to vaccination in antibiotic-treated infants

The Bloom Infant Probiotic (BIP) Study
Project Status: Commencing
Project administered by: Flinders University

We are looking for healthy newborn babies who received antibiotics in the first 28 days of life to participate in a study to see if a probiotic can improve your baby's immune system response to vaccinations.

You and your infant may be eligible if you are an adult (18+), and your baby received antibiotics in the first 28 days of life.

What's involved?

  • A recruitment interview (in person or online) to determine eligibility of your infant
  • If eligible, your baby will be randomly assigned (like flipping a coin) to receive either a probiotic or placebo* supplement. You won't know which.
  • Administer the study supplement (1 per day) to your baby at home for 14 days.
  • Collect 4 stool (poo) samples from your baby at home that can be mailed back to the study team by prepaid envelope.
  • Have your baby receive their routine vaccinations through the study.
  • Attend our clinic to have 3-4 blood samples (a teaspoon amount each time) collected from your baby over their first 12 months of life to measure their immune response.

*The same as the probiotic but without the active ingredient.

To reimburse costs associated with attending this study you will receive a payment of $300 for completing the entire study. To find out more, please contact the study team on bipstudy@sahmri.com.

Developed with input from the BIP Consumer Advisory Group, approved by the Women's and Children's Hospital HREC, and funded by the Women's and Children's Hospital Foundation.

Project Leader

PARTNERING INSTITUTIONS

Women's & Children's Hospital, Flinders Medical Centre, Flinders University, SA Health

This project is funded by the Women's & Children's Hospital Foundation

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SAHMRI is located on Kaurna Country. We pay respects to the Kaurna people of the Adelaide Plains and to all Aboriginal and Torres Strait Islander people. We are committed to embracing knowledge and culture as we continue our working journey to incorporate Aboriginal health research across all of our themes and further reconciliation.

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"Tirki nguta tappa tangka marninithi"

(Learning and knowledge are the pathway to alter the mind)

- Uncle Lewis Yerloburka O’Brien, Kaurna Elder