Dr Esther Camp-Dotlic

Dr. Esther Camp-Dotlic is a developmental and cell biologist with over 10 years of national and international research experience in the field or transgenesis and the study of molecular mechanisms, which control embryonic and mesenchymal stem cell migration, proliferation and differentiation. She has considerable experience with various animal models investigating molecular mechanisms in early embryo development, cardiac development, skeletal bone remodelling, cranial bone development and bone pathologies. Her current work is focused on understanding the molecular mechanisms that control mesenchymal stem/progenitor cell (MSC) proliferation and differentiation during skeletal bone remodelling and cranial development. The projects that she coordinates include: investigating the role of the transcription factor Twist-1 and microRNAs in bone marrow and cranium derived MSC and a pre-clinical trial to develop novel therapeutics to treat cranial bone defects in children. This work could potentially translate into alternative treatments for patients with bone related diseases, such as craniosynostosis and osteosarcoma.