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Genomics Staff Scientist (single cell and spatial transcriptomics)

Posted date: 07 / 11 / 2023

Important information

  • Reference SAHMRI636
  • Employment type FTC - Full-time Contract
  • Location SAHMRI North Terrace
  • Applications close Friday, 22 Dec 2023
  • Contact
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Full-Time, 2 Year Contract

The South Australian Genomics Centre (SAGC) is a multi-institutional, national genomics and bioinformatics facility that is supported by Bioplatforms Australia (BPA), The Government of South Australia and our partner institutes and universities through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS). The SAGC has consolidated genomics and bioinformatics expertise in the state, with a group of more than 12 genomics and bioinformatics staff working side-by-side to deliver innovative genomics and bioinformatics solutions across all areas of genomics research, including agriculture, healthcare and ecology. The SAGC is headquartered in the iconic South Australian Health and Medical Research (SAHMRI) building in the Adelaide CBD.

An exciting opportunity now exists for a Genomics Staff Scientist focused on the single cell genomics and spatial transcriptomics fields to join the SAGC team.

The facility has been pioneering in the spatial transcriptomics and single-cell genomics fields since its inception. The SAGC is the only genomics facility in Australia to offer the ultra-high throughput MGI T7 sequencing service, which enables the only spatial transcriptomics method that achieves both centimetre-level panoramic field of view and nanoscale resolution. The SAGC is also one of only three 10x Genomics reference sites in Australia and is equipped with the complete tool set to carry out spatial transcriptomics and single-cell genomics projects utilising its leading technologies.

The successful candidate will play a vital role in the implementation and development of cutting-edge technologies in fields such as spatial transcriptomics (e.g. STOmics, Xenium, Visium, CytAssist), single-cell genomics (e.g. 10x Genomics, Parse Biosciences), short-read sequencing (platforms such as MGI and Illumina), long-read sequencing (e.g. Oxford Nanopore, PacBio), where the SAGC is in a unique position to continue to play a leading role.

To flourish in this role, you will need to be able to work across multiple different projects and to possess excellent organisational and time-management skills. In addition, in-depth knowledge of current genomics technologies and a collaborative mindset will be key to be successful in this role. Your career progression will be supported and you will be encouraged to participate conferences and seminars to keep up with the up-to-date technologies.

About the role

Key responsibilities include:

  • Implementing and developing novel spatial and single cell genomics workflows within the facility.
  • Working closely with other external research groups to carry out complex experiments in areas such as single-cell genomics, spatial transcriptomics and related technologies.
  • Working as part of a wider team.
  • Participating in manuscript preparation as well as grant applications.
  • Playing an active role in the design and execution of complex experimental methods for users.
  • Liaising with SAGC’s team of genomics and bioinformatics staff to improve and develop processes to enhance SAGC’s services.
  • Maintaining accurate written records of all experiments undertaken, following the SAGC Platform Quality Management System (PQMS).
  • Participating in the day-to-day running of the facility including ordering laboratory supplies, generating standard operating procedures (in liaison with the PQMS Manager), and maintaining safe laboratory practices through work health and safety measures.

About You

The successful candidate will possess the following key attributes:

Essential Criteria

  • Doctoral degree in a relevant area (e.g. Biomedical, environmental or agricultural genomics disciplines) or equivalent experience.
  • A minimum of 3 years’ professional experience working in a genomics-related field.
  • Demonstrated experience with molecular biology techniques including handling of nucleic acids and high standard of laboratory skills.
  • Hands-on experience in handling various types of tissue sectioning, such as fresh-frozen and FFPE.
  • Have a broad understanding and hands-on experience in at least two of the following areas:
    • Sample Receipt: documenting, handling and storage for DNA/RNA samples.
    • Sample QC: sample quantification and qualification.
    • Library generation: library generation with various sample types (e.g. bulk RNA, whole-genome DNA, amplicon, single cell, tissue sections).
    • Library preparation: pooling, denaturation and loading flowcells before sequencing.
    • Sequencing: platforms operation and maintenance such as Illumina Nextseq, Illumina Miseq, MGI-G400, MGI-T7, Chromium Controller.
  • Extensive knowledge and experience implementing novel workflows in a laboratory setting, particularly in the spatial transcriptomics and single-cell genomics fields.
  • Effective interpersonal skills with a demonstrated ability to network and liaise with stakeholders and staff.


Desirable Criteria

  • Prior hands-on experience in cell processing and microscopy
  • Prior working experience in NATA-accredited laboratories

Everything we do is underpinned by our core values and our institute is dedicated to grow a culture that pursues, enables and demands research excellence. We are proud of the work we do and work hard as a team to make a positive difference to the community.  Our values of excellence, innovation, courage, integrity and teamwork are what help us achieve our goals. If these are also your values and goals, apply today.

As a not-for-profit organisation, SAHMRI employees can access salary packaging options up to $15,900. Salary packaging lets you pay for things like the everyday costs of living with money from your salary before tax. This reduces your taxable income, meaning you could pay less tax and take home more of what you earn. For more information on salary packaging please see the Maxxia website.

For a copy of the position description, please click here.

For more information, please contact Dr Sen Wang at

Applications close: 11:29pm ACST Friday 22nd December 2023

Aboriginal and Torres Strait Islander people are strongly encouraged to apply

SAHMRI is a member of the Athena SWAN Science in Australia Gender Equity program. We have been awarded Bronze status for our commitment to advancing the careers of women, trans and gender diverse individuals in STEMM.

Applications close Friday, 22 Dec 2023


Apply now

Equity & Diversity at SAHMRI

At SAHMRI, we live our commitment to equity and diversity every day: respecting people as individuals and valuing differences to create a working environment that is fair and flexible, promotes personal and professional growth and benefits from the capabilities of a diverse workforce.

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